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CDE,MS,RD
Advanced Glycation Endproducts
Section:  General Diabetes

Do any of you consider AGEs when counseling patients about insulin sensitivity? Has anyone seen compelling research that AGE-restricted diets are important in diabetes treatment or cancer prevention?

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Re: Advanced Glycation Endproducts

WOW, thank you for bringing this topic up! Unprocessed/minimally processed foods properly prepared can be more powerful than previously thought in reducing inflammation and insulin resistance. I accessed the text:

The diabetics assigned to this AGE-restricted diet enjoyed a 35 percent drop in blood insulin levels, well beyond the decreases achieved by their previous therapeutic regimen.

This drop in insulin resistance was associated with improved markers of inflammation and a restoration of compromised immune-system performance.

The results showed that even a modest cut in consumption of AGEs improved insulin resistance in adults with diabetes.

The authors noted:

"The potentially negative effects of traditional forms of cooking and food processing have typically remained outside the realm of health considerations. However, accumulation of AGEs due to the systematic heating and processing of foods offers a new explanation for the adverse health effects associated with the Western diet, reaching beyond the question of overnutrition."

 

Re: Advanced Glycation Endproducts

I agree Bonnie. It is impressive. Helen Vlassara has a book coming out in a few weeks. It's called the AGE-Less Way.

 

Re: Advanced Glycation Endproducts

I have to learn how to search "ALL" when I post a question....I had just asked this question under a NUTRITION HEADING...but I'm glad to read that there is someone else discussing this topic.  I had read about slow cooking (after I bought my first crock pot a few years ago.)  The intersting issue that was identified was that a loss of nutrients of the water soluble vitamins.  Have you read any work about this??